Search results for "Smoking initiation"
showing 4 items of 4 documents
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
2010
Smoking is a leading global cause of disease and mortality(1). We established the Oxford-GlaxoSmithKline study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association with smoking-related behavioral traits. Our final data set included 41,150 individuals drawn from 20 disease, population and control cohorts. Our analysis confirmed an effect on smoking quantity at a locus on 15q25 (P = 9.45 x 10(-19)) that includes CHRNA5, CHRNA3 and CHRNB4, three genes encoding neuronal nicotinic acetylcholine receptor subunits. We used data from the 1000 Genomes project to investigate the region using imputation, which allowed for analysis of virtually all common SNPs in the region and offered a …
Is educational differentiation associated with smoking and smoking inequalities in adolescence? A multilevel analysis across 27 European and North Am…
2016
This study aims to determine whether educational differentiation (i.e. early and long tracking to different school types) relate to socioeconomic inequalities in adolescent smoking. Data were collected from the WHO-Collaborative 'Health Behaviour in School-aged Children (HBSC)' study 2005/2006, which included 48,025 15-year-old students (Nboys = 23,008, Ngirls = 25,017) from 27 European and North American countries. Socioeconomic position was measured using the HBSC family affluence scale. Educational differentiation was determined by the number of different school types, age of selection, and length of differentiated curriculum at the country-level. We used multilevel logistic regression t…
Inattentiveness, parental smoking and adolescent smoking initiation
2004
Aims To examine how adolescents’ inattentive behaviour, together with parental smoking patterns, predicts smoking initiation by age 14. Design, settings A prospective, longitudinal study: baseline at ages 11–12, follow-up at age 14. A population-based sample of Finnish twins, born 1983–1987, with parents and classroom teachers as additional informants. Two groups were formed, allocating the co-twins of each family into separate groups: the study sample and a replication sample. Participants Twin individuals (n = 4552), aged 11–12 at baseline and 14 (average 14.04 years) at follow-up. Measurements At baseline, inattentiveness was assessed with the Multidimensional Peer Nomination Invento…
Factors associated with the subjective health complaints among adolescents: Results from the ASSO Project
2019
Objectives. Subjective health complaints (e.g. headache and feeling low) are common among adolescents. The objective of this study was to identify the factors associated with the subjective health of adolescents from a population-based point of view. Material and methods. A sample of 712 students was recruited within the web-based Project ASSO (Adolescents and Surveillance System for the Obesity prevention), funded by the Italian Ministry of Health and piloted in Palermo. A 0-100 quantitative score (arbitrarily named "psychosomatic malaise index") based on the frequency of occurrence of seven subjective health complaints was created and used as outcome; socio-demographic characteristics, me…